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Are you looking for an opportunity to put your organizational and technical skills to the test?
Do you want to be part of a dynamic and creative-thinking lab?
Here is your chance to contribute to science that makes a difference!
To strengthen our excellent research team, we are looking for a highly organized person with laboratory experience in mouse work, hematology and flow cytometry. In this responsible role, you will participate on multiple projects in the lab and will perform in vivo experiments in the mouse, in the context of genome editing, hematopoiesis and leukemia. You will be part of a multidisciplinary competence center for pediatric cancer research and you will have a direct influence on the development of new cancer therapies.
The Seruggia group (www.seruggialab.com) is interested in gene regulation in the context of pediatric cancer, and focuses on the study of non-coding regulatory sequences (enhancers) as well as protein complexes involved in the control of gene expression. We use genome editing (CRISPR screenings, CRISPRi/a, dense mutagenesis), chromatin profiling (ChIP-seq, CUT and RUN, ATAC-seq), proteomics, mouse models and computational approaches to identify and characterize mechanisms of leukemia development. Our research is funded by a Starting Grant from the ERC and investigates the link between sequence variation at non-coding regions and leukemia development.
Relevant publications: Seruggia et al. Molecular Cell 2019; Sher, Hossain, Seruggia et al. Nature Genetics 2019; Seruggia et al. Scientific Reports 2020; Debruyne et al. Nature 2019; Seruggia et al Nucleic Acids Research 2015.
Your responsibilities
- Develop new mouse models: you will perform experiments in vivo including blood stem cell transplantation and genome editing.
- Evaluate new targets: you will test the contribution of genes and mutations in disease and assess the activity of novel compounds on blood development and leukemia.
- Become an integral member of our team: you will contribute with your work, ideas and observations in a highly collaborative environment.
Your profile
What you bring for this position:
- A Master’s degree in Biology, Biotechnology or related subjects
- Strong expertise in mouse work is required (including a FELASA certification or equivalent title)
- Collaborative mindset and motivation to work in an international, interdisciplinary environment
- Team player with strong communication skills and a proactive “getting things done’’ mentality
Our offer
Does this sound interesting? This is our offer to you:
- A challenging role in a meaningful, inspiring, and international environment
- An outstanding working atmosphere in young and dynamic team (find more information on Kununu and Glassdoor)
- Opportunity to learn new techniques and acquire highly specialized training
- Flexible working hours, discounted lunch and other great benefits
- Great location in the center of Vienna, a capital of biomedical research in Europe with excellent quality of life
- A fair and attractive salary package starting at € 2.800,- gross (14x per year) on full-time basis with a view to increase based on your qualification and experience
Who we are
The St. Anna Children's Cancer Research Institute (St. Anna CCRI) is located in the heart of Vienna, the most livable city in the world and one of the most important sites for biomedical research in Europe. St. Anna CCRI is a multidisciplinary and internationally networked center of excellence whose goal is to contribute to a sustainable improvement in the cure rates of childhood and adolescent cancers through innovative research and development. Due to the close cooperation between clinic and research, St. Anna Children's Cancer Research offers the ideal environment for cutting-edge research at a high international level and its implementation in clinical practice.
St. Anna CCRI is an equal opportunity employer. We value diversity and are committed to providing a work environment of mutual respect to everyone without regard to race, colour, religion, national origin, age, gender identity or expression, disability, or any other characteristic protected by applicable laws, regulations and ordinances.
Find more information here: https://ccri.at/
Your application
We are looking forward to your application! Applications should at least contain your Curriculum Vitae including contacts for references and a cover letter.
The application deadline is the 15.08.2023. Applications will be reviewed on a rolling basis until the position is filled.
